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Breast and colorectal, two main cancers

V3.5

Breast and colorectal, two main cancers we see, Let’s break them down, so clear and free. TNM staging, it’s the key, Tumour, Nodes, Metastasis, easy as can be. Breast cancer types, let’s explore, Ductal, lobular, and so much more. Invasive carcinoma, spreads around, In women most common, let’s get it down. Fine needle aspiration, biopsy too, Core biopsy gives a clearer view. DCIS, high risk in the breast, LCIS, moderate, both must be addressed. Paget’s disease, nipple involved, Invasive malignancy, problem unsolved. Grading cancers, morphology and rate, Three scores together, determine fate. Triple negative, no ER, PR, HER2, Aggressive in young, but treatments few. ER/PR positive, better prognosis ahead, Tamoxifen helps, as it’s often said. Colorectal cancer, very common here, 14% of all cancers, we hold it near. Proximal colon, symptoms can hide, Distal and rectal, harder to confide. FOBT, faecal occult blood test, Screening programme, it’s the best. Colonoscopy and biopsy, diagnosis made, Adenocarcinomas, how they're displayed. Stages of spread, direct invasion, Lymphatic, haematogenous, coelomic persuasion. Treatment varies by location and type, Surgery’s mainstay, let’s get it right. Microsatellite instability, MSI high, Mismatch repair genes, we ask why. Lynch syndrome, HNPCC, Hereditary risk, know the key. Adenomas in colon, benign at first, Tubular, villous, they can be the worst. Adenoma-carcinoma, step-wise we see, From benign to malignant, it’s a sequence, believe me. Breast and colorectal, cancer’s the game, Understand the types, the tests, the name. From biopsy to treatment, staging too, Knowledge is power, now it’s all up to you.