: pulse inversion. Contrast. Harmonic imaging does NOT listen at the frequency you sent. It deliberately ignores the fundamental and tunes in to the overtone — that's the trick. Inject a contrast agent and you've released millions of microbubbles — each a gas bell smaller than a red cell. Hit them with sound and they don't just reflect, they RING, far more dramatically than stiff tissue. Blood that was nearly invisible suddenly glows. Pulse inversion is the magician's version: send a pulse, then send its exact upside-down mirror. The linear echoes cancel to nothing, but the nonlinear harmonics survive and add up. What's left is pure overtone. Takeaways. Microbubbles ring loudly. Tissue rings in harmonics at two f-naught. Listen at the harmonic for a cleaner image; pulse inversion isolates it. Self-check. One: at what frequency does harmonic imaging listen? Two: why is the harmonic image cleaner than the fundamental? Three: what does pulse inversion cancel, and what survives? Chapter Ten, done.